Test Highlights:

  • DNA samples can be collected easily at home using buccal (cheek) swabs.
  • Dogs can be DNA tested at ANY age using the buccal swabs.
  • DNA results are emailed within 5 business days of receipt of the samples
  • Test fee is $58 (US) per canine, multi-test discounts may apply

Progressive Retinal Atrophy, Progressive Rod-Cone Degeneration (PRA-prcd)

Progressive Retinal Atrophy, Progressive Rod-Cone Degeneration (PRA-prcd) is inherited as an autosomal recessive disease. Degeneration of both rod and cone photoreceptor cells of the retina of PRA-prcd affected dogs usually occurs 3 to 5 years of age or later.  Affected dogs initially experience night blindness and loss of peripheral vision.  As the disease progresses, complete blindness will occur in time.  Different breeds and individual dogs may experience variation in the age and rate of the disease progression.

DDC Veterinary is offering DNA Testing for PRA-prcd (PRCD c.5G>A). Breeders have an accurate, convenient, and affordable tool to help them avoid producing PRA-prcd affected offspring and significantly reduce the gene frequency in future generations.

This mutation affects several breeds like the Chesapeake Bay Retriever, Chihuahua, Cocker Spaniel, Golden Retriever, Labrador Retriever, Poodle and Yorkshire Terrier.  To see if this test is available for your breed, use the Order Canine Tests by Breed tool to see a complete list of DNA tests.


There are 3 possible genotypes reported for Progressive Retinal Atrophy, Progressive Rod-Cone Degeneration:

  • CLEAR (those having 2 copies of the normal allele and appear to be normal)
  • CARRIER (those having 1 copy of the normal allele and 1 copy of the PRA-prcd mutation but appear to be normal)
  • AT RISK (those having 2 copies of the PRA-prcd mutation and will develop blindness over time)

It is important to note, although carriers will not show clinical signs of the disease, if used for breeding, they will likely pass on the mutation 50% of the time, therefore a carrier to carrier mating will likely result in producing affected pups in about 25% of the offspring.

Results are based upon the specific prcd c.5G>A mutation. There are multiple types of PRA caused by other gene mutations.  Clear results for PRA-prcd only pertain to the prcd c.5G>A mutation tested.  It will not detect if a dog has any other form of Progressive Retinal Atrophy


Canine DNA Frequently Asked Questions >


For more information about how these test results can be used for registration, contact the Orthopedic Foundation for Animals (OFA).