von Willebrand's Disease (vWD) DNA Testing

Test Highlights:

  • DNA samples can be collected easily at home using buccal (cheek) swabs.
  • Dogs can be DNA tested at ANY age using the buccal swabs.
  • DNA results are emailed within 5 business days of receipt of the samples.
  • Test fee is $58 (US) per canine, multi-test discounts may apply.

October Special! Save $20 on this test through October 31, 2019. Type breed name in the blue box to get started. 

von Willebrand’s Disease Type I (vWD I)

von Willebrand’s Disease is the most common inherited bleeding disorder in canines. There are three classifications of vWD that are based on the concentration and nature of plasma von Willebrand Factor. Type I von Willebrand’s is characterized by abnormally low production of protein found in the vWF blood which is a key factor in the process of clotting a damaged blood vessel and is usually milder and more variable in form than the other types.

vWD is inherited as an autosomal recessive disorder. Therefore, dogs that carry one (1) copy of the vWD mutation may exhibit a reduction in the amount of plasma vWF, but are not likely symptomatic. A carrier x carrier mating will likely produce some affected offspring. The DNA Test for von Willebrand’s disease is an accurate, convenient, and affordable tool to help avoid producing vWD affected offspring.

DNA testing for von Willebrand’s Disease Type I is available for the following breeds: Bernese Mountain Dog, Coton de Tulear, Doberman Pinscher, Drentsche Patrijschond, German Pinscher, Goldendoodle, Kerry Blue Terrier, Labradoodle, Manchester Terrier, Papillion, Pembroke Welsh Corgi, Poodle, Stabyhoun

There are 3 possible genotypes reported for von Willebrand’s Disease Type I :

  • CLEAR (those having 2 copies of the normal allele and appear to be normal).
  • CARRIER (those having 1 copy of the normal allele and 1 copy of the vWD mutation but appear to be normal).
  • AFFECTED (those having 2 copies of the vWD I mutation and are at risk of suffering a severe bleeding incident).

Results are based upon the specific von Willebrand’s Type I mutation (c.7437G>A). Clear results for vWD I only pertain to the specific mutation tested. It will not detect if a dog has any other form of bleeding disorder.


Canine DNA frequently asked questions

For more information about how these test results can be used for registration, contact the Orthopedic Foundation for Animals (OFA) or the Canine Health Information Center (CHIC).